Cardinol plus 5mg/50mg

Cardinol Plus 5mg/50mg Tablets is a clinically approved medication developed by Mankind Pharma Ltd to effectively control hypertension (high blood pressure) and manage angina pectoris (chest pain due to heart disease). It combines two well-established active pharmaceutical ingredients—Amlodipine Besilate (5 mg) and Atenolol (50 mg)—each belonging to a different class of cardiovascular drugs. Together, they offer a comprehensive and synergistic approach to reducing blood pressure and maintaining cardiac stability.

Composition and Mechanism of Action

Amlodipine Besilate (5 mg): A long-acting calcium channel blocker (CCB) that works by relaxing the smooth muscles of blood vessels. This relaxation widens the arteries, allowing blood to flow more freely, which in turn reduces the strain on the heart and lowers blood pressure.

Atenolol (50 mg): A cardio-selective beta-blocker that reduces heart rate, myocardial contractility, and cardiac output. It helps the heart beat more efficiently and prevents the heart from overworking, thus lowering blood pressure and controlling chest pain.

By combining these two mechanisms—vasodilation (from amlodipine) and decreased cardiac output (from atenolol)—Cardinol Plus provides dual protection and control against high blood pressure and related cardiovascular risks.

Therapeutic Uses

Treatment of Hypertension: Helps maintain optimal blood pressure, reducing the risk of heart attack, stroke, and kidney damage.

Management of Angina Pectoris: Reduces the frequency and severity of chest pain by improving oxygen delivery to the heart.

Prevention of Cardiac Complications: Long-term use lowers the risk of heart failure and other heart-related disorders.

Benefits of Cardinol Plus 5mg/50mg

Offers dual-action therapy in a single tablet, improving patient compliance.

Provides sustained and consistent blood pressure control over 24 hours.

Reduces heart rate and vascular resistance simultaneously.

Minimizes the need for multiple medications in hypertensive patients.

Well-tolerated with minimal adverse effects when taken under medical supervision.

Dosage and Administration

The typical dosage is one tablet daily, taken at the same time each day with or without food, as prescribed by a healthcare provider. The dosage may vary depending on individual response and medical condition. Regular monitoring of blood pressure and heart rate is advised during therapy.

Precautions and Warnings

Consult a doctor before use if you have kidney, liver, or heart disorders.

Avoid abrupt discontinuation, as it may cause a sudden rise in blood pressure or worsening of angina.

Use caution while driving or operating machinery, as the drug may cause dizziness.

Not recommended during pregnancy or breastfeeding unless prescribed by a physician.

Inform your doctor about other ongoing medications to avoid drug interactions.

Possible Side Effects

Most side effects are mild and temporary. Common ones include:

Fatigue, dizziness, or lightheadedness

Swelling of feet or ankles (due to Amlodipine)

Slow heart rate (due to Atenolol)

Cold hands and feet, headache, or mild nausea

If any side effect persists or worsens, medical advice should be sought promptly.

Storage Instructions

Store in a cool, dry place below 25°C.

Keep away from direct sunlight and moisture.

Keep out of reach of children.

Conclusion

Cardinol Plus 5mg/50mg is a trusted, doctor-recommended combination therapy for long-term management of hypertension and cardiovascular disorders. Its balanced formulation ensures effective control of blood pressure and cardiac rhythm while improving overall cardiovascular health. When used under proper medical supervision, Cardinol Plus promotes heart efficiency, prevents serious heart complications, and enhances quality of life for patients managing chronic heart or blood pressure issues.